98-00 has developed a novel framework for evaluating biofunctional materials. This evidence-based methodology guides the development and assessment of engineered biomaterials, directing them toward scalable solutions that deliver demonstrated human health benefits. Created in collaboration with leading experts in bioengineering and materials science, the framework provides a comprehensive and structured approach to evaluating materials with advanced functionality—such as smart responsiveness, transdermal delivery mechanisms, and protective properties designed to shield against environmental stressors—all with particular emphasis on interactions with human skin.
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The framework integrates internationally recognized testing standards (ISO, OECD, ASTM) alongside validated dermatological methodologies to deliver clear, transparent evaluation protocols. It employs tiered endpoint categorization, calibrated scoring thresholds, and systematic assessment processes to precisely analyze material properties. These components enable detailed classification of materials based on their proven biosafety, biological activity, real-world performance, and measurable contributions to healthspan.